For more than five million Venezuelans, crossing international borders has become an imperative to gain security and a livelihood that their country has failed to assure. These migrants, particularly young women and children are vulnerable to many depredations, criminal acts, and the risk of becoming trafficking victims for forced labor and sexual slavery. This article focuses on State responsibility for migrant populations and looks at conditions in Venezuela that caused massive migration, the conditions in Colombia as a host State, the uncertain status of Venezuelan migrants in Colombia, and the presence of human trafficking and its impact on the migrant population